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26 décembre 2018 Non Par admin

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les dysfonctionnements érectiles il peut être proposé au patient l’utilisation d’un vacuum qui est une pompe à dépression
il existe également différents traitements
les médicaments oraux 
ces médicaments agissent rapidement, mais uniquement en présence d’excitation sexuelle
un cylindre est placé sur le pénis et crée une dépression qui fait rockerect preis
affluer le sang dans le pénis et pour obliger le sang à rester dans les corps caverneux on met en place un anneau qui. serre la base du pénis, anneau qui est retiré à la fin du rapport et il ne doit pas être pilule pour bander en pharmacie
laissé en place plus de 30 minutes
disponibles sur ordonnance, les traitements oraux doivent être pris au plus tard entre 20 minutes et une heure avant le rapport sexuel
c’est un traitement mécanique sans aucun médicament et qui est très efficace mais ne peut être proposé qu’à des patients sélectionnés
leur. durée d’action est variable selon le médicament (de 12 à 36 heures)
ces médicaments ne sont actuellement pas remboursés par l’assurance maladie
un examen clinique de l’état du cœur et des vaisseaux sanguins est indispensable avant leur prescription
en effet, ces médicaments doivent rockerect test
être utilisés avec beaucoup de précautions chez les personnes présentant des troubles cardiaques
maladies cardiovasculaires
ces médicaments ne doivent jamais être utilisés en association les uns avec les autres dans l’espoir d’obtenir de meilleurs résultats
attention : ces médicaments sont incompatibles avec les traitements de l’angine de poitrine de la famille des vasodilatateurs et

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distribution of the testosterone excretion and also with the large differences in testosterone excretion between koreans and swedes
a number of conspicuous interethnic differences between asian and caucasian men in reproductive endocrinology are still lacking an explanation [see van houten and gooren (1) for a review]
for example, the rate of prostate cancer is 2–40 times higher among caucasian than asian men (2)
differences between these groups in sensitivity to male contraception regimens have also been described
thus, asian men respond to exogenous contraceptive androgens with a higher suppression of spermatogenesis than caucasian men (3, 4)
it is also established that the urinary testosterone to epitestosterone ratio, commonly used in international antidoping test programs, is considerably lower in asians than caucasians, leading to difficulties in interpretation of the results
the limited effect of androgen doping on testosterone excretion in asian populations increases the risk of false-negative results (5)
much of the current interest in androgen research is focused on the role of testosterone in prostate cancer (6) and the detection and effects of doping to improve the physical achievements in sports (7)
whereas relatively much is known about the function of testosterone and its effects in target organs, little is known about its disposition including urinary excretion
testosterone is excreted mainly as glucuronide conjugates (8) after glucuronidation by uridine diphospho (udp)-glucuronosyl transferases (ugt)
these enzymes have a key role in the homeostasis of a number of endogenous molecules including steroid hormones (9), and they facilitate their excretion in bile and urine (9)
there are seven members of the ugt2b subfamily
they have a preference for glucuronidation of bile acids, steroids, fatty acids, carboxylic acids, phenols, and carcinogens (9–11)
one of these, ugt2b17, was found to be particularly active in androgen glucuronidation (12)
a gene deletion in this enzyme gene was recently described (13), and it was further characterized by wilson et al
the physiological consequences of this deletion polymorphism are unknown
given this background, we decided to study the urinary excretion pattern and circulating concentrations of testosterone and other androgens in relation to the ugt2b17 genetic polymorphism in nonathlete volunteers of caucasian and asian ethnic descent
our results show that this polymorphism is strongly associated with the bimodal distribution of the testosterone excretion as well as the large differences in androgen excretion between asians and caucasians
these data may have relevance for understanding the mechanisms behind prostate disease and are of great importance for the antidoping test programs
seventy-four unrelated korean male subjects aged 21–39 yr (mean 26
5 yr) were recruited among medical students and personnel at inha university hospital
their health status was assessed by medical questionnaire
all subjects in this study participated voluntarily after giving informed consent
the study was approved by the institutional review board at inha university hospital and the ethics committee at the karolinska university hospital
the caucasian sample included 122 men aged 18
6 yr), who were randomly selected from the gothenburg osteoporosis and obesity determinants study, which was initiated with the aim to determine both environmental and genetic factors for bone and fat mass, in which study subjects were randomly identified using national population registers, contacted by telephone, and asked to participate in this study
that study was approved by the ethics committee at gothenburg university, and written informed consent was obtained from all participants
in the korean population, venous blood was obtained from the cubital vein and collected in edta tubes (for dna and plasma extraction)
plasma was immediately extracted at 4 c and kept frozen at −20 c until analysis
in the swedish population, whole blood was obtained from the cubital vein and collected in edta tubes (for dna extraction) and gel-containing tubes (for serum extraction)
serum was extracted using standardized procedures, immediately frozen, and stored at −80 c until analysis
the serum and plasma samples were analyzed in the same laboratory using the same assay, and according to the manufacturer of the immunoassay kit for steroid analyses in the circulation (orion diagnostica, espoo, finland), identical results are obtained in serum and plasma
spot urine samples were collected and immediately frozen at −20 c
to minimize any influence of diurnal variation, all blood and urine samples were collected between 1400 and 1930 h
urinary unconjugated steroids (typically < 1% of glucuronide fraction) + steroid glucuronides were determined by gas chromatography-mass spectrometry after hydrolysis of the conjugates with β-glucuronidase as described (15) with minor modifications (16) within- and between-assay coefficients of variation were less than 7% and less than 10% for all steroids analyzed testosterone was measured by spectria [125i]-coated tube ria, and shbg was measured by [125i] immunoradiometric assay (orion diagnostica) non-shbg-bound testosterone (nst, sum of unbound + albumin-bound testosterone) was used as an index of biologically active testosterone as proposed by pardridge (17) apparent concentrations of nst were calculated from values for total testosterone, shbg, and a fixed albumin concentration of 42 g/liter by successive approximation using a computer program based on an equation system derived from the law of mass action (18) additional analysis of 17ohp was performed in subgroups of the populations consisting of 29 koreans and 22 swedes by competitive ria using a commercial kit obtained from cis bio international, gif-sur-yvette, france (ohp-ct) detection limits and within- and between-assay coefficients of variation were for testosterone 0 all the serum and plasma samples were analyzed in the same laboratory to avoid interassay variation genotyping was essentially performed as previously described (14) the deletion-specific primers (j markers) and the exon 6-specific primers were used in a standard pcr-protocol (amplitaqdna polymerase, applied biosystems, foster city, ca), and the products were identified in a 2% agarose gel due to low dna concentrations, some of the swedish samples were analyzed with sybrgreen master mix (applied biosystems), and the product formations were followed on an abi prism 7700 additionally these products were also confirmed on a gel in dna samples from heterozygous individuals [deletion (del)/insertion (ins)], a product from both the reactions appeared, whereas in individuals homozygous for the deletion allele (del/del) and individuals homozygous for ugt2b17 insertion

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